Swiss Master Roger Federer will face off against John Isner in the second singles match for Switzerland in the Davis Cup tie against the United States of America over the weekend.

The former world number one will face Isner after world number eight Mardy Fish finishes his first match against Swiss star Stanislas Wawrinka. Federer is the hands down favorite for the match against Isner and with the American trailing the record Grand Slam holder 2-0 in career match ups; it is almost a foregone conclusion that he will be swept aside on the clay court.

Although the first two matches between the pair were on hard court surfaces, the clay provides all new challenges for the American who aims to play quick points against the Fed Express. Isner commented that his strength in the match will be his fast serves and he will try hard to avoid the long rallies against Roger Federer, which is not the best thing to go up against for any player. He also added that he needs to be aggressive in order to stand a chance in the match.

On the other hand, Fish, who holds the advantage in career match ups over Wawrinka aims to get the Americans off to flying start with victory over the second highest ranked Swiss player. Federer and Wawrinka, who won the Gold Medal in the 2008 Beijing Olympic Games for Switzerland in the Doubles event, will face off against Mike Bryan and 19 year old Ryan Harrison, who is in line for his Davis Cup debut in the match.

However, the eyes of the home crowd will be on the second match of the singles competition which will see crowd favorite Roger Federer take the court in front of his home fans after almost a two year gap.

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